ABSTRACT
The planned digital textbook Human Parasitology, the first of its kind, published by People's Medical Publishing House is an important medical education effort that features the inte-gration of digital resources. This paper introduces the digital textbook construction goal, namely using paper-based textbook for five-year undergraduates as blueprint to reasonably display the digital re-sources based on the features of the discipline. The advantages of this digital approach over traditional paper-based textbook in demonstrating parasitic morphology, lifecycle, pathogenesis, diagnosis, epi-demiology and control are discussed. Valuable experiences in planning and constructing this digital textbook are to be shared.
ABSTRACT
Objective To explore possible associations between host polymorphism of HLA classⅡgenotypes and advanced hepatosplenic schistosomiasis japonica.Methods 45 advanced schistosomiasis patients(experimental group) and 44 age,and sex,matched patients with chronic schistosomiasis(control group) from the same area were investigated for their HLA class II gene DRB genotypes by genotyping the alleles using microarray DNA chip.The correlation of allele frequencies to advanced hepatosplenic schistosomiasis was compared for the two groups.Results HLA,DRB1*04x exhibited markedly higher frequency in advanced patients than that in control group(P